The first week of March Madness is in the books and it was exactly as described, MADNESS! With the most upsets in the first 2 rounds in recent memory, almost everyone's brackets are busted.

If you want to "stay in the game" and place a bet on the Sweet 16 check out our odds and picks.

South Region

(11) Loyola Ramblers vs. (7) Nevada Wolf Pack

(9) Kansas State Wildcats vs. (5) Kentucky Wildcats

East Region

(5) West Virginia Mountaineers vs. (1) Villanova Wildcats

(3) Texas Tech Red Raiders vs. (2) Purdue Boilermakers

West Region

(9) Florida State Seminoles vs. (4) Gonzaga Bulldogs

(7) Texas A&M Aggies vs. (3) Michigan Wolverines

Midwest Region

(5) Clemson Tigers vs. (1) Kansas Jayhawks

(11) Syracuse Orange vs. (2) Duke Blue Devils

With so many upsets coming out of the first and second round of the NCAA Tournament, bettors may want to lay down a big bet on an underdog and take a chance at winning big. The next upset is anyone's guess, but here are the odds on each Sweet 16 team winning the NCAA Championship.

+325 Duke
+450 Villanova
+700 Kentucky
+700 Gonzaga
+800 Michigan
+850 Kansas
+1600 West Virginia
+1600 Purdue
+2200 Texas Tech
+2500 Texas A&M
+2500 Clemson
+2500 Nevada
+2800 Kansas State
+4000 Florida State
+5000 Loyola-Chicago
+6600 Syracuse

Best USA Sportsbooks for March Madness Betting